For me, climbing and downhill ... not a lot of flat.
Personally, I prefer wheels that are reasonably light, non aero, and if they have bladed spokes, only lightly bladed. Reasonably light for obvious reasons. Non-aero because that minimizes weight at the periphery and reduces the moment of inertia around the rotational axis, and also makes them more stable in crosswinds. Non-bladed spokes for the same reason (crosswind susceptibility).
I've had some bad experience with rear hubs in the past, so for that ... conventional and robust design is preferable.
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