Throw disc brakes into the mix and it become even more of a pita. My easiest bike has rear facing horizontal dropouts which eliminates most of the fighting with the RD. You just pull the chain straight back and slip it on the cogs and slide the rear wheel in. I know the new clutched Sram RDs for mtn bikes allow you to lock the RD which would make things a hell of a lot easier. Both my mtn bikes are still rocking old 9 speed setups though.
https://www.youtube.com/watch?v=XcFkUdKOLK0