I very much doubt that my experiences will relate in any way to your experience with this saddle and your particular bike and riding posture.
To answer your question, generally, I don't get too much change in comfort from a change in saddle. But I'm very particular about the saddle type. I really only ride two types of saddle: slung leather or racing-style. For slung leather (think Brooks, Ideale, Fujita, Gyes, etc.), I'm extremely careful with the nose angle, setback and design width to match the application (utility bike, commuter, more aggressive, etc.).
For racing-style, I have a set of criteria that define which saddles I'm willing to try: firm, flat, narrow. So, these eliminate 95% of the saddles sold. The remaining saddles can all be comfortable for me, as long as that nose angle (pitch) is set up correctly. If I swap between any of these saddles, my experience is generally favorable right from the get-go. Subtle adjustments are still needed to correct for variations between them, though.