Then, the discussion should focus on Leptin, Ghrelin, PGC-1α, SIRT1, AMPK and others rather than GIGO. How does exercise timing, extent, and intensity when combined with specific foods result in improved metabolism. Certainly, genetics play a role but taping one's mouth shut isn't a bad start.
Intermittent fasting and long Z2 rides are helpful. Cold thermogenesis is helpful. Keeping carb ingestion down helps, especially avoiding spikes in insulin helps a lot.
More importantly, how do fat people break the cycle of leptin and insulin resistance.