It is modern enough that any curent/recent mechanical road drivetrain will work. 8, 9, 10, 11sp- all fine.
Pick the one you want and just make sure all components are compatible.
As for tires, use a hex wrench to check the space between the frame and tires at the chainstays, seat tube, brake bridge, and fork crown. You need to keep at least a few mm of space all around the tire to account for road debris, wheel wobble, etc.