Originally Posted by
MoAlpha
NSAIDs and blood volume reduction from dehydration both produce signals that decrease kidney blood flow. The combination can reduce flow to the point where permanent kidney damage (acute tubular necrosis) occurs.
One time use, or over a period of time?
I know of TT guys that will take 800 mg prior to an hour TT, and that usually means no water/fluids ingested, other that prior and post TT.