Originally Posted by hokiefyd

You'll just want to clean up the inside of the tire and rim as much as you personally care to do for peace of mind, cosmetics, etc. A bit of dried sealant here and there shouldn't bother a tube.

I have tubes in my Surly Nates and they're perfectly fine. The tubes certainly have some mass to them but, as with you, an extra pound or two on the bike certainly isn't going to make or break me. I'm a 240 pound rider and I ride my Nates down to silly low pressures with tubes and they're fine. That's of the benefits of a fat bike and you don't have to have a tubeless setup to enjoy the pleasures of low air pressure.