Thanks for posting CFB. I'm still young at 70.
I'll look into this and ask my pharmacist wife too. The only supplement I've ever found to be pretty much universally supported by the medical community is collagen peptides. I've been adding this to my mid-day smoothie for the last year and take it on faith that it's providing some long term benefit. If there are no contraindications to taking HMB, I could easily work it into my diet. I've lost over 20 lbs in the last 10 months by cutting out junk and 1. only coffee for breakfast (gives me about a 15+ hour fasting), 2. a smoothie for lunch (yogurt, almond milk, bananas, blueberries, spinach, whey protein, psyllium fiber, oat bran and collagen peptides), and 3. a normal, healthy supper. A good thread may be smoothie recipes, if it hasn't been done already.