what you need to know:
- spacing... probably 135mm between dropouts for a road disc rear wheel... just go ahead and buy metric tape measure, if you don't have one already (front spacing is 100mm)
- dropout/axle... quick release vs thru axle, 9mm vs 12mm vs 15mm
- drivetrain... can your new wheel handle your (11-sp?) cassette
if these things are the same between new and old, you're all set.