Originally Posted by GhostRider62

Sometimes

Balance of mTOR and AMPK pathways

Can't or shouldn't always eat like a pig and shouldn't also be catabolic all the time.

Skinny old people live a long time but are frail. Fat young people may be strong but they die early. A good balance can lead to a longer healthy lifespan. Fall and early winter would be when I would use various techniques to activate mTOR and lose weight, this time also corresponds to when any exercise would be low aerobic. I have no interest to live to 150 like SInclair but it would be nice to be strong, lean and have good balance and mobility into my late 80's and then just drink the good stuff and smoke cigars until around 95.