Regarding intermittent fasting (IF) versus general calorie restriction (CR) for longevity, this study with mice found that restricting eating to the daily "active period" was about twice as effective as eating the same calories around the clock.
Findings:
- CR increased lifespan by 10%
- IF increased lifespan by 20%
- IF subjects had higher insulin sensitivity and blood sugar stability
- IF got deadly diseases at far more advanced ages
-- Acosta-Rodriguez et al,
Circadian alignment of early onset caloric restriction promotes longevity in male C57BL/6J mice, Science 2022
Mice aren't humans, but 20% vs. 10% is quite a difference.